Amphotericin B 1397-89-3 Antibiotic
Uku:T/T, L/C
Kumu Huahana:Kina
Awa moku:Pekina/Shanghai/Hangzhou
Hiki ke hana:100kg / mahina
Kauoha(MOQ):25 kg
Ka manawa o waena o ka hoʻomaka a i ka wā pau:3 Nā lā hana
Kūlana mālama:me ka ʻeke hau no ka lawe ʻana.E mālama i ka 2-8 ℃ no ka wā lōʻihi.
Mea paʻa:pahu
Nui pūʻolo:25kg / pahu
ʻIke palekana:ʻAʻole nā mea weliweli
Hoʻolauna
ʻO Amphotericin B, hiki ke kapa ʻia ʻo Fungizone a i ʻole Ambisome, he polyene antifungal antibiotic i hoʻokaʻawale ʻia mai ka moʻomeheu moʻomeheu o Streptomycesnodosus.Hoʻokaʻawale ʻia e ʻelua ʻāpana me A a me B, akā ʻoi aku ka liʻiliʻi o kahi ʻāpana no ka antifungal i hoʻohana ʻole ʻia, no laila hoʻohana nā kānaka i ka ʻāpana B i kapa ʻia ʻo Amphotericin B.
He lāʻau antifungal i hoʻohana ʻia no nā maʻi fungal koʻikoʻi a me ka leishmaniasis.He ʻelua hoʻohana ʻokoʻa ma ka waha a me ka injection.
ʻO Amphotericin B ka mea koho mua no ka maʻi leʻaleʻa hohonu ma muli o kona ākea antifungal spectrum.Loaʻa iā ia ka hana i nā fungals e like me cryptococcus, coccidium, candida albicans a me blastomycetes, a pēlā aku.
ʻO nā hōʻailona koʻikoʻi e like me: 1. Ka mālama ʻana i nā fungals e like me cryptococcosis, North American blastomycosis, disseminated candidiasis, coccidiosis a me histoplasmosis.2. Lapaʻau ʻana i ka mucormycosis i hoʻokumu ʻia e kekahi mau fungal e like me Rhizopus, colporium, endomycetes a me frog fecal mold.3. Ka lapaʻau ʻana i ka sporotrichosis i hana ʻia e ka sporotrichosis schenckii.4. Lapaʻau ʻana i ka aspergillosis i hana ʻia e Aspergillus fumigatus.5. He kūpono ka hoʻomākaukau ʻana no ka pigmented mycosis.He kūpono no ka maʻi fungal ʻili ma hope o ke kuni ʻana, ka ʻāpana hanu ʻo Candida a me Aspergillus a i ʻole ka maʻi cryptococcus, a me ka hana no ka maʻi maʻi fungal corneal.
ʻO nā hopena ʻaoʻao maʻamau ka hopena me ke kuni, ke anu, a me ke poʻo ma hope koke o ka hāʻawi ʻia ʻana o ka lāʻau lapaʻau, a me nā pilikia puʻupaʻa.Hiki ke loaʻa nā hōʻailona maʻi me ka anaphylaxis.ʻO nā hopena koʻikoʻi ʻē aʻe e pili ana i ka potassium haʻahaʻa koko a me ka mumū o ka puʻuwai.ʻIke ʻia he palekana i ka wā hāpai.Aia kahi ʻano lipid i loaʻa i ka hopena haʻahaʻa o nā hopena ʻaoʻao.Aia ia i loko o ka papa polyene o nā lāʻau lapaʻau a hana i kekahi hapa ma ka hoʻopili ʻana i ka membrane cell o ka haʻiki.Pono e makaʻala ka hoʻohana ʻana i ka wā i loaʻa ai nā kūlana, no ka hoʻohana palekana pono e hahai i ka ʻōlelo aʻo mai nā limahana lapaʻau.
Hōʻikeʻike oral Grade (In House Standard)
| 'ikamu | Hōʻike |
| Ka nana aku | Melemele a ʻalani-melemele ka pauka, ʻaʻole a ʻaneʻane ʻole. |
| ʻIkepili | IR, HPLC |
| pH | 4.0-6.0 |
| Nalo ma ka maloo | ≤5.0% |
| Lehu Sulfate | ≤3.0% |
| Na mea pili | ≤0.5% |
| 303nm | haumia A (Amphotericin A) ≤5.0% He haumia ʻike ʻole ʻia ≤1.0% |
| 383nm | haumia B (Amphotericin X1) ≤4.0% He haumia ʻike ʻole ʻia ≤2.0% |
| Huina paumaele | ≤15.0% |
| Nā mea hoʻoheheʻe koena | Methanol ≤0.3% Acetone ≤0.5% |
| Hoʻāʻo | ≥850 amphotericin B ʻāpana/mg no ka mea maloʻo. |
Hōʻikeʻike oral Grade (In House Standard)
| 'ikamu | Hōʻike |
| Ka nana aku | Melemele a ʻalani pauda ʻole. |
| ʻIkepili | IR, HPLC |
| Ke koena ma ka ʻā | ≤0.5% |
| Nā mea pili |
|
| Ma 303nm | Amphotericin A ≤2.0% |
| He haumia ʻike ʻole ʻia ≤1.0% | |
| Ma 383nm | Amphotericin X1 ≤4.0% |
| He haumia ʻike ʻole ʻia ≤2.0% | |
| Huina haumia | ≤15.0% |
| Nā mea hoʻoheheʻe koena | Acetone ≤0.5% |
| Methanol ≤0.3% | |
| palena microbiological | Aerobic microbial helu ≤1000cfu/g |
| Molds & hū ≤100cfu/g | |
| Escherichia coli ʻAʻole i loko o 1g | |
| ʻO nā endotoxins bacteria | <1.0EU/mg |
| Hoʻāʻo | ≥850 amphotericin B units/mg, helu ʻia ma ke kumu maloʻo |
