ʻO nā paipu Laboratory

Huahana

Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer

ʻO ka wehewehe pōkole:

Nā huaʻōlelo like:CP-690550 (Tofacitinib citrate);(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2 -hydroxy-1,2,3-propanetricarboxylate

Helu CAS:540737-29-9

ʻAno maikaʻi:ma ka hale

ʻAno Molekala:C16H20N6O.C6H8O7

Kaumaha formula:504.49


Huahana Huahana

Huahana Huahana

Uku:T/T, L/C
Kumu Huahana:Kina
Awa moku:Pekina/Shanghai/Hangzhou
Hiki ke hana:100kg / mahina
Kauoha(MOQ):25 kg
Ka manawa o waena o ka hoʻomaka a i ka wā pau:3 Nā lā hana
Kūlana mālama:Hoʻopaʻa ʻia ma kahi anuanu, maloʻo, ka lumi wela.
Mea paʻa:pahu
Nui pūʻolo:25 kg/pahu
ʻIke palekana:ʻAʻole nā ​​mea weliweli

Tofacitinib citrate

Hoʻolauna

ʻO Tofacitinib, he lāʻau lapaʻau i hoʻohana ʻia e mālama i ka maʻi rheumatoid, psoriatic arthritis, a me ka ulcerative colitis.

Hoʻohana ʻia ka Tofacitinib citrate no ka mālama ʻana i nā poʻe mākua me ka maʻi rheumatoid maʻalahi a paʻakikī loa i loaʻa ka pane kūpono ʻole i ka methotrexate.

Hōʻike ʻia ʻo Tofacitinib citrate no ka mālama ʻana i ka maʻi rheumatoid maʻemaʻe a koʻikoʻi (RA) i loko o nā pākeke i pane kūpono ʻole, a i ʻole ka poʻe intolerant i hoʻokahi a i ʻole nā ​​​​lāʻau antirheumatic hoʻololi i ka maʻi.

Hōʻike (ma ka hale)

'ikamu

Hōʻike

Ka nana aku

ʻO ka pauka kristal keʻokeʻo keʻokeʻo a keʻokeʻo paha

ʻIkepili

IR, HPLC

Wai

≤1.5%

Na mea pili

TOFA 06 ≤0.15%

Tofacitinib trans isomer ≤0.15%

Tofacitinib dehydrogenated ≤0.15%

ʻO kēlā me kēia haumia ʻike ʻole ≤0.10%

Huina haumia: ≤1.0%

Nā mea hoʻoheheʻe koena

Ethanol ≤5000ppm

Benzene ≤2ppm

Toluene ≤890ppm

Chlroroethane ≤1000ppm

N,N-Dimethylformamide ≤800ppm

Palladium ≤10ppm

Dichloromethane ≤600ppm

Lehu sulphated

≤0.1%

Metala Kaumaha

≤10ppm

Chrial HPLC

3S, 4S tofacitinib ≤0.15%

ʻIke (ma ke kumu anhydrous) 98.0-102.0%


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