ʻO nā paipu Laboratory

Huahana

Tacrolimus monohydrate 109581-93-3 Antibiotic

ʻO ka wehewehe pōkole:

Nā huaʻōlelo like:FK-506;FK506 monohydrate

Helu CAS:109581-93-3

ʻAno maikaʻi:USP43

ʻAno Molekala:C44H69NO12

Kaumaha formula:822.04


Huahana Huahana

Huahana Huahana

Uku:T/T, L/C
Kumu Huahana:Kina
Awa moku:Pekina/Shanghai/Hangzhou
Hiki ke hana:1kg / mahina
Kauoha(MOQ):1g
Ka manawa o waena o ka hoʻomaka a i ka wā pau:3 Nā lā hana
Kūlana mālama:Hoʻopaʻa ʻia ma kahi anuanu, maloʻo, ka lumi wela.
Mea paʻa:hue, ʻōmole
Nui pūʻolo:1g/puʻu, 5/puʻu, 10g/puʻu, 50g/puʻu, 500g/puʻu
ʻIke palekana:UN 2811 6.1/PG 3

ʻO Tacrolimus monohydrate

Hoʻolauna

ʻO Tacrolimus, kahi lāʻau immunosuppressive.Ma hope o ka hoʻololi ʻana o ke kino allogeneic, ʻoi aku ka maʻalahi o ka hōʻole ʻana o ke kino.No ka hoʻohaʻahaʻa i ka hopena o ka hōʻole ʻana o ke kino, hāʻawi ʻia ka tacrolimus.Hiki ke kūʻai ʻia ka lāʻau lapaʻau ma ke ʻano he lāʻau lapaʻau i ka mālama ʻana i nā maʻi T-cell-mediated e like me eczema a me psoriasis.Hiki ke hoʻohana ʻia no ka mālama ʻana i ka maʻi maʻi maka maloʻo i nā pōpoki a me nā ʻīlio.

Kāohi ʻo Tacrolimus i ka calcineurin, ka mea i komo i ka hana ʻana o ka interleukin-2, he mole e hoʻoikaika i ka hoʻomohala ʻana a me ka hoʻonui ʻana o nā pūnae T, ma ke ʻano he ʻāpana o ke kino i aʻo ʻia (a i ʻole adaptive).

Hōʻike (USP43)

'ikamu

Hōʻike

Ka nana aku

Keʻokeʻo a aneane keʻokeʻo crystalline pauda

ʻIkepili

IR, HPLC

Ka hoʻoheheʻe

Hiki ke hoʻoheheʻe ʻia i ka methanol, hiki ke hoʻoheheʻe ʻia i ka N,N dimethylformamide a me ka waiʻona, hiki ke hoʻoheheʻe ʻia i ka wai.

Ke koena ma ka ʻā

≤0.10 %

ʻO nā mea haumia kino

(ka hana-2)

Ascomycin 19-epimer ≤0.10 %

Ascomycin ≤0.50 %

Desmethyl tacrolimus ≤0.10 %

Tacrolimus 8-epimer ≤0.15 %

Tacrolimus 8-propyl analog ≤0.15 %

He haumia ʻike ʻole -I ≤0.10 %

He haumia ʻike ʻole -II ≤0.10 %

He haumia ʻike ʻole -III ≤0.10 %

Huina haumia ≤1.00 %

ʻO ka hoʻololi ʻana (ma ke ʻano he kumu)

(10mg/ml i ka N,Ndimethylformamide)

-110.0° ~ -115.0°

Waiwai (na KF)

≤4.0%

Nā mea hoʻoheheʻe koena (na GC)

Acetone ≤1000ppm (Ma ka hale)

Di-isopropyl ether ≤100ppm (Ma ka hale)

Ethyl ether ≤5000ppm

Acetonitrile ≤410ppm

Toluene ≤890ppm

Hexane ≤290ppm

ʻO ka hoʻāʻo microbial (ma ka hale)

Huina aerobic microbial helu ≤100cfu/gm

Huina hū a me ka helu helu ≤10cfu/gm

Pono ʻole nā ​​mea ola kino (Pathogens) (E.coil, salmonella sps., S.aureus. Pseudomonas aeruginosa)

ʻIke (e HPLC) (ma ke kumu anhydrous a me ka solvent free)

98%~102%


  • Mua:
  • Aʻe: