ʻO Orlistat 96829-58-2 Antiobesity Diet supplement
Uku:T/T, L/C
Kumu Huahana:Kina
Awa moku:Pekina/Shanghai/Hangzhou
Hiki ke hana:800kg / mahina
Kauoha(MOQ):25 kg
Ka manawa o waena o ka hoʻomaka a i ka wā pau:3 Nā lā hana
Kūlana mālama:Hoʻopaʻa ʻia ma kahi anuanu, maloʻo, ka lumi wela.
Mea paʻa:pahu
Nui pūʻolo:25kg / pahu
ʻIke palekana:ʻAʻole nā mea weliweli
Hoʻolauna
ʻO Orlistat kahi hana lōʻihi a ikaika i ka gastrointestinal lipase inhibitor.He pauda keʻokeʻo a kokoke i ke keʻokeʻo i ka wela lumi, hiki ʻole ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i loko o ka chloroform, a hiki ke hoʻoheheʻe ʻia i ka ethanol.Hoʻopau ia i ka enzyme ma o ka hana ʻana i nā paʻa covalent me nā wahi serine ikaika o ka lipase ʻōpū a me ka lipase pancreatic i loko o ka ʻōpū a me ka ʻōpū liʻiliʻi.
ʻO Orlistat kahi ʻano o ka lipase inhibitor hoʻemi kaumaha.He hydrated derivative o lipstatin, hiki ke hoʻemi i ka absorption o ka momona meaʻai a hoʻemi i ke kaumaha.He ikaika a koho ʻia kēia huahana i ka gastric lipase a me ka pancreatic lipase, ʻaʻohe hopena i nā enzyme digestive ʻē aʻe (amylase, trypsin, chymotrypsin) a me ka phospholipase, ʻaʻole pili i ka absorption o nā carbohydrates, proteins a me phospholipids.Hoʻopau ia i ka enzyme ma o ka hoʻopaʻa ʻana o ka covalent me nā koena serine ma nā wahi hana o ka gastric lipase a me ka pancreatic lipase i loko o ka ʻōpū o ka ʻōpū, kaohi i ka hydrolysis o triacylglycerol, hoʻemi i ka lawe ʻana o ka monoglyceride a me ka momona momona, a pēlā e hoʻomalu ai i ke kaumaha o ke kino.ʻAʻole hoʻopili ʻia ka lāʻau lapaʻau e ka gastrointestinal tract, a hiki ke hoʻohuli ʻia ka inhibition o ka lipase.
Loaʻa i kēia huahana ka hana o ka hoʻoponopono ʻana i nā lipids koko.Hiki iā ia ke hoʻemi i ka triglyceride a me ka lipoprotein cholesterol haʻahaʻa i ka serum o nā maʻi obese a hoʻonui i ka ratio o ka lipoprotein kiʻekiʻe kiʻekiʻe i ka lipoprotein haʻahaʻa haʻahaʻa.
Ke hui pū ʻia ka orlistat me kahi meaʻai haʻahaʻa haʻahaʻa, kūpono ia no ka mālama lōʻihi o ka poʻe momona a me ke kaumaha, me ka poʻe i hoʻomohala i nā mea pili i ka momona.Loaʻa iā ia ka hana hoʻomalu paona lōʻihi e like me ka pohō kaumaha, mālama paona a me ka pale hou ʻana.Hōʻike maopopo ka lāʻau lapaʻau he mea pono loa ka hana hoʻomalu kaumaha no ka hoʻohana lōʻihi i ka wā e hui pū ai me ka ʻai a ma hope o hoʻokahi hola o ka ʻai.
Hiki i ka Orlistat ke hoʻemi i ka nui o ka nui o nā mea pili i ka momona a me nā maʻi e pili ana i ka momona, me ka hypercholesterolemia, type II diabetes, impaired glucose tolerance, hyperinsulinemia, hypertension, a hoʻemi i ka momona momona i loko o nā kino.
Hōʻike (USP42)
| 'ikamu | Hōʻike |
| ʻIkepili | HPLC, IR |
| ʻO ka hoʻololi ʻana i ka optical kikoʻī | -48.0°~-51.0° |
| ʻAno wai | ≤0.2% |
| Nā mea pili I | Orlistat pili pūhui A ≤0.2% |
| Nā mea pili II | ʻO Orlistat pili pūhui B ≤0.05% |
| Nā mea pili III
| Formylleucine ≤0.2% |
| Orlistat pili pūhui C ≤0.05% | |
| Orlistat hāmama apo epimer ≤0.2% | |
| D-Leucine orlistat ≤0.2% | |
| He haumia ʻike ʻole ʻia ≤0.1% | |
| Nā mea pili IV | Orlistat pili pūhui D ≤0.2% |
| ʻO Orlistat open ring amide ≤0.1% | |
| Nā mea pili V | Orlistat pili pūhui E ≤0.2% |
| Huina haumia (I a V) | ≤1.0% |
| Nā mea hoʻoheheʻe koena | Methanol ≤0.3% |
| EtOAc ≤0.5% | |
| n-Heptana ≤0.5% | |
| Ke koena ma ka ʻā | ≤0.1% |
| Nā metala kaumaha e like me Pb | ≤20ppm |
| ʻIke ʻia e HPLC | 98.0% ~ 101.5% (ma ka anhydrous, solvent-free kumu) |
